| Date | Location | Result | |
| Dec 30, 2021 | Nashville, TN | Purdue 48, Tennessee 45 | Box score |
| Nov 27, 2021 | Knoxville, Tennessee | Tennessee 45, Vanderbilt 21 | Box score |
| Nov 20, 2021 | Knoxville, Tennessee | Tennessee 60, South Alabama 14 | Box score |
| Nov 13, 2021 | Knoxville, Tennessee | Georgia 41, Tennessee 17 | Box score |
| Nov 06, 2021 | Lexington, Kentucky | Tennessee 45, Kentucky 42 | Box score |
| Oct 23, 2021 | Tuscaloosa, Alabama | Alabama 52, Tennessee 24 | Box score |
| Oct 16, 2021 | Knoxville, Tennessee | Ole Miss 31, Tennessee 26 | Box score |
| Oct 09, 2021 | Knoxville, Tennessee | Tennessee 45, South Carolina 20 | Box score |
| Oct 02, 2021 | Columbia, Missouri | Tennessee 62, Missouri 24 | Box score |
| Sep 25, 2021 | Gainesville, Florida | Florida 38, Tennessee 14 | Box score |
| Sep 18, 2021 | Knoxville, Tennessee | Tennessee 56, Tennessee Tech 0 | Box score |
| Sep 11, 2021 | Knoxville, Tennessee | Pittsburgh 41, Tennessee 34 | Box score |
| Sep 02, 2021 | Knoxville, Tennessee | Tennessee 38, Bowling Green 6 | Box score |